
Bridging the intimacy gap

Premature ejaculation
Premature ejaculation is a distressing condition characterized by a loss of ejaculatory control, causing men to ejaculate before or shortly after penetration, often within less than a minute.
In the general population, women typically take three times longer than men to reach climax, leading to 75% of women not achieving orgasm during partnered intercourse

Premature Ejaculation at a Glance

Types of premature ejaculation (PE)
The International Society of Sexual Medicine (ISSM) recognises four subtypes of PE:
Lifelong PE:
characterized by PE symptoms present since first sexual intercourse
Acquired PE:
characterized by PE symptoms beginning after a period of normal ejaculatory function
Natural variable PE:
characterized by short ejaculatory latency which occurs irregularly and inconsistently with some subjective sense of diminished control of ejaculation
Subjective PE:
Characterized by subjective perception or imagined short ejaculation latency time, and/or diminished or lacking ability to control ejaculation”
Treatment of premature ejaculation
There are currently no FDA-approved pharmacological treatments for premature ejaculation. Kadence Bio is developing KH-001 as an on-demand orally administered treatment. Treatment options include:
Drug Treatment
Licensed (not US) and off-label oral and topical treatments
Non-Drug Treatment
Psychosexual counselling, education and behavioural treatments
Combination
A combination of drug and non-drug treatment

"Partners of these men also suffer, and report sexual dissatisfaction and frustration, as well as problems in the relationship."
Dr Andrea Burri, Psycho-sexologist
